Histochemical Studies of Hydroxysteroid Dehydrogenases in Delayed Implanting Mouse Blastocysts
نویسندگان
چکیده
منابع مشابه
Genetic manipulation of 11beta-hydroxysteroid dehydrogenases in mice.
11beta-hydroxysteroid dehydrogenases (HSDs) interconvert active 11-hydroxy glucocorticoids (cortisol, corticosterone) and their inert 11-keto derivatives (cortisone, 11-dehydrocorticosterone). 11beta-HSD type 1 is a predominant reductase that regenerates active glucocorticoids in expressing cells, thus amplifying local glucocorticoid action, whereas 11beta-HSD type 2 catalyzes rapid dehydrogena...
متن کامل11β-Hydroxysteroid Dehydrogenases in the Regulation of Tissue Glucocorticoid Availability
The regulation of tissue-specific actions of glucocorticoids (GCs) goes far beyond the effects of the fluctuation of their circulating levels and can be controlled by local intracellular en‐ zymes. In the past few years, evidence is being gathered not only on the relevance of such enzymes to GC physiological actions but also on their involvement in the pathophysiology of certain chronic disease...
متن کاملGenetic manipulation of 11 -hydroxysteroid dehydrogenases in mice
Paterson, Janice M., Jonathan R. Seckl, and John J. Mullins. Genetic manipulation of 11 -hydroxysteroid dehydrogenases in mice. Am J Physiol Regul Integr Comp Physiol 289: R642–R652, 2005; doi:10.1152/ajpregu.00017.2005.— 11 -Hydroxysteroid dehydrogenases (HSDs) interconvert active 11-hydroxy glucocorticoids (cortisol, corticosterone) and their inert 11-keto derivatives (cortisone, 11-dehydroco...
متن کامل11β-Hydroxysteroid Dehydrogenases and Hypertension in the Metabolic Syndrome
The metabolic syndrome describes a clustering of risk factors-visceral obesity, dyslipidaemia, insulin resistance, and salt-sensitive hypertension-that increases mortality related to cardiovascular disease, type 2 diabetes, cancer, and non-alcoholic fatty liver disease. The prevalence of these concurrent comorbidities is ~ 25-30% worldwide, and metabolic syndrome therefore presents a significan...
متن کاملHydroxysteroid Dehydrogenases – Localization, Function and Regulation in the Testis
© 2012 Kotula-Balak et al., licensee InTech. This is an open access chapter distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Hydroxysteroid Dehydrogenases – Localization, Function and Regulation in the Te...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nihon Chikusan Gakkaiho
سال: 1984
ISSN: 1346-907X,1880-8255
DOI: 10.2508/chikusan.55.499